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BOOK SUMMARY :

Description retaining the successful approach found in the previous volume in this series the inventors and primary developers of drugs that successfully made it to market tell the story of the drugs discovery and development and relate the often twisted route from the first candidate molecule to the final marketed drugthe first volume of the book series successful drug discovery is focusing on new drug discoveries during the last decade from established drugs to recently introduced drugs of all kinds small molecule peptide and protein based drugsin summary successful drug discovery volume 2 doi 1010029783527800315 wiley online library covers eleven case histories in six different therapeutic areas it came on sale as a book and e book in december 2016 the cost of the latter is slightly lowerthe cyclic amp signaling pathway exploring targets for successful drug discovery review kuo yan 1 2 li na gao 1 2 yuan lu cui 1 2 yi zhang 1 2 and xin zhou 1 2 1 research center of traditional chinese medicine tianjin university of traditional chinese medicine tianjin 300193 pr chinabibliography includes bibliographical references and index contents preface xiii list of contributors xvii part i hdac inhibitor anticancer drug discovery 1 1 from dmso to the anticancer compound saha an unusual intellectual pathway for drug design 3ronald breslow 11 introduction 3 12 the discovery of saha vorinostat 4 13 clinical trials 7 14 follow on research selective hdac

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